![]() ![]() ![]() ![]() In the 1960s, 1970s, and 1980s, before the virus was discovered and HCV screening of the blood supply was standard practice, HCV infection was expanding worldwide. Like HIV, HCV is primarily transmitted through parenteral exposures. In 2012, 22,972 Americans died of liver cancer, 28,972 were newly diagnosed, and HCV-related deaths surpassed all 60 other nationally notifiable diseases combined. In the United States, in 2007, the number of deaths related to HCV overtook the number of human immunodeficiency virus (HIV)-related deaths. An estimated 2.7–3.9 million Americans live with HCV infection. Globally, liver cancer is the second most common form of cancer death, and in the United States, occurrences are increasing at a higher rate than any other form of cancer except thyroid cancer. Of these, 15–30% will be diagnosed with liver fibrosis or cirrhosis, and 5% will die from cirrhosis or hepatocellular carcinoma (HCC). Approximately 80% of HCV infections develop into the chronic state. Worldwide, almost 3% of people are infected with hepatitis C virus (HCV). ![]()
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